Progressive nodular histiocytoma

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Progressive Nodular Histiocytoma (pruh-gres-iv noh-dyuh-lar his-tee-oh-sy-toh-muh) is a rare type of cutaneous histiocytosis characterized by the progressive development of multiple nodules on the skin.

Etymology

The term "Progressive Nodular Histiocytoma" is derived from the Latin progressivus meaning "advancing", nodulus meaning "small knot", and histiocytoma which is derived from the Greek histio meaning "tissue" and cytoma meaning "tumor".

Definition

Progressive Nodular Histiocytoma is a rare form of non-Langerhans cell histiocytosis, a group of disorders characterized by an abnormal increase in the number of immune cells known as histiocytes. These histiocytes form nodules or lesions on the skin that progressively increase in number over time.

Symptoms

The primary symptom of Progressive Nodular Histiocytoma is the appearance of multiple nodules on the skin. These nodules are typically brown or red in color and can vary in size. They are most commonly found on the trunk, arms, and legs, but can appear anywhere on the body.

Diagnosis

Diagnosis of Progressive Nodular Histiocytoma is typically made through a combination of clinical examination and histopathological analysis of a skin biopsy. The presence of histiocytes in the skin biopsy is a key diagnostic feature.

Treatment

Treatment for Progressive Nodular Histiocytoma is primarily aimed at managing symptoms and preventing complications. This may include surgical removal of the nodules, chemotherapy, or radiation therapy.

Related Terms

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