Proscillaridin
Proscillaridin
Proscillaridin (pronunciation: pro-sci-lar-i-din) is a cardiac glycoside, a type of compound that has a specific effect on the heart muscle. It is derived from plants of the genus Scilla and Drimia.
Etymology
The term "Proscillaridin" is derived from the genus name Proscilla, a variant of Scilla, the plant from which it is extracted. The suffix "-idin" is commonly used in the naming of glycosides.
Function
Proscillaridin works by inhibiting the sodium-potassium ATPase pump, which leads to an increase in intracellular calcium. This increase in calcium causes the heart muscle to contract more forcefully and efficiently, improving the symptoms of heart failure.
Related Terms
- Cardiac Glycoside: A type of compound that has a specific effect on the heart muscle.
- Sodium-Potassium ATPase: An enzyme found in the plasma membrane of all animal cells, which functions to establish and maintain the electrochemical gradients of sodium and potassium ions.
- Heart Failure: A chronic condition in which the heart doesn't pump blood as well as it should.
- Scilla: A genus of about 50 to 80 bulb-forming perennial herbs in the family Asparagaceae, subfamily Scilloideae, native to woodlands, subalpine meadows, and seashores throughout Europe, Africa and the Middle-East.
- Drimia: A genus of flowering plants, native to Africa.
External links
- Medical encyclopedia article on Proscillaridin
- Wikipedia's article - Proscillaridin
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