Prothionamide
Prothionamide
Prothionamide (pronounced pro-thi-on-amide) is an antibiotic medication primarily used in the treatment of tuberculosis. It is classified under the drug class of thioamides.
Etymology
The term "Prothionamide" is derived from its chemical structure. The prefix "pro-" is from the Greek "pro" meaning "before", indicating the presence of a propyl group. "Thionamide" refers to the class of organic compounds it belongs to, which contain a sulfur atom (thio-) and an amide group (-amide).
Usage
Prothionamide is used in combination with other antitubercular drugs to treat tuberculosis, particularly multi-drug resistant strains. It is not typically used as a first-line treatment, but is reserved for cases where other treatments have failed or are not suitable.
Side Effects
Common side effects of Prothionamide include gastrointestinal disturbances such as nausea, vomiting, and diarrhea. More serious side effects can include hepatotoxicity, neurotoxicity, and hypersensitivity reactions.
Related Terms
- Tuberculosis: An infectious disease caused by the bacterium Mycobacterium tuberculosis.
- Thioamides: A class of organic compounds that contain a sulfur atom and an amide group.
- Antitubercular drugs: Medications used to treat tuberculosis.
- Hepatotoxicity: Toxicity to the liver.
- Neurotoxicity: Toxicity to the nervous system.
- Hypersensitivity reactions: Allergic reactions to a drug or other substance.
External links
- Medical encyclopedia article on Prothionamide
- Wikipedia's article - Prothionamide
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