Pseudoallergy

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Pseudoallergy

Pseudoallergy (/ˈsjuːdoʊˈælərdʒi/) is a term used to describe a reaction that mimics a true allergy, but occurs without the involvement of the immune system. The term is derived from the Greek words 'pseudes' meaning false and 'allergia' meaning allergy.

Definition

A pseudoallergic reaction, also known as a non-allergic hypersensitivity or intolerance, is a reaction that has the same symptoms as an allergic reaction but is not caused by an immune response. Instead, it is often caused by the direct stimulation of mast cells, which release histamine and other inflammatory substances.

Symptoms

The symptoms of a pseudoallergy can be similar to those of a true allergy and can include urticaria (hives), angioedema (swelling), rhinitis (runny nose), asthma, anaphylaxis, and gastrointestinal symptoms.

Causes

Pseudoallergies can be triggered by a variety of substances, including certain foods, drugs, and dyes used in medical imaging. Unlike true allergies, pseudoallergies do not involve IgE antibodies and do not require prior exposure to the substance.

Treatment

Treatment for pseudoallergies typically involves avoiding the triggering substance and managing symptoms. Antihistamines and corticosteroids may be used to control symptoms.

See also

External links

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