Purple glove syndrome
Purple Glove Syndrome
Purple glove syndrome (PGS) (/ˈpɜːrpl ɡlʌv sɪnˈdroʊm/) is a rare but serious complication that can occur following intravenous Phenytoin administration. The condition is characterized by progressive distal limb Edema, discoloration, and pain.
Etymology
The term "purple glove syndrome" is descriptive, referring to the discoloration and swelling that often resembles a hand wearing a purple glove. The exact origin of the term is unknown.
Symptoms
The symptoms of purple glove syndrome typically occur within hours to days following phenytoin administration. They include:
- Pain and discomfort in the affected limb
- Swelling or edema
- Discoloration, ranging from pink to purple
- Possible progression to Necrosis or tissue death if not treated promptly
Causes
Purple glove syndrome is most commonly associated with the intravenous administration of the antiepileptic drug phenytoin. The exact mechanism is not fully understood, but it is believed to be related to the drug's propensity to precipitate in the bloodstream and cause direct vascular injury.
Treatment
Treatment of purple glove syndrome primarily involves discontinuation of intravenous phenytoin. Other measures may include elevation of the affected limb, warm compresses, and in severe cases, surgical intervention may be necessary.
Related Terms
See Also
External links
- Medical encyclopedia article on Purple glove syndrome
- Wikipedia's article - Purple glove syndrome
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski