Ravulizumab

From WikiMD

Ravulizumab
Monoclonal antibody
Type?
SourceTemplate:Infobox drug/mab source
TargetComplement component 5
Gene therapy
Clinical data
Trade namesUltomiris
Other namesALXN1210
Routes of
administration
intravenous infusion
ATC code
Physiological data
Legal status
Legal status
  • In general: rx only
Pharmacokinetic data
Metabolismvarious proteases
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Chemical and physical data
FormulaC6430H9888N1696O2028S48
Molar mass144.9 g/mol g·mol−1
Data page

Ravulizumab (ALXN1210) (INN:[1] Ultomiris) is a humanized monoclonal antibody designed for the treatment of paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome.

This drug was developed by Alexion Pharmaceuticals, Inc.[2]

It was approved by the US Food and Drug Administration in December 2018.[3] In April 2019, the European CHMP of EMA recommended the granting of a conditional marketing authorisation for ravulizumab.[4]

References

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