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Template:Infobox drug/title
Monoclonal antibody
SourceTemplate:Infobox drug/mab source
TargetComplement component 5
Clinical data
Trade namesUltomiris
[[Regulation of therapeutic goods |Template:Engvar data]]Template:Infobox drug/licence
Template:Infobox drug/pregnancy category
Routes of
intravenous infusion
ATC code
Legal status
Legal statusTemplate:Infobox drug/legal status
Pharmacokinetic data
Metabolismvarious proteases
CAS Number
PubChem CID
PubChem SID
PDB ligand
E number{{#property:P628}}
CompTox Dashboard (EPA)
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Chemical and physical data
FormulaTemplate:Infobox drug/chemical formula
Molar massTemplate:Chem molar mass
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Ravulizumab (ALXN1210) (INN:[1] Ultomiris) is a humanized monoclonal antibody designed for the treatment of paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome.

This drug was developed by Alexion Pharmaceuticals, Inc.[2]

It was approved by the US Food and Drug Administration in December 2018.[3] In April 2019, the European CHMP of EMA recommended the granting of a conditional marketing authorisation for ravulizumab.[4]


  1. World Health Organization (2017). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 117" (PDF). WHO Drug Information. 31 (2).
  2. Statement On A Nonproprietary Name Adopted By The USAN Council - Ravulizumab, American Medical Association.
  3. FDA approves new treatment for adult patients with rare, life-threatening blood disease
  4. "EMA Positive Opinion - Ultomiris / ravulizumab, April 26, 2019" (PDF). ema.europa.eu. Retrieved 11 May 2019.

Template:Monoclonals for immune system

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