Retroperitoneal fibrosis
Retroperitoneal fibrosis (pronunciation: reh-troh-peh-rih-toh-nee-al fai-broh-sis), also known as Ormond's disease, is a rare disorder characterized by the presence of inflammatory and fibrous tissue behind the peritoneum (the membrane lining the abdominal cavity). This fibrous tissue often surrounds the aorta and ureters, potentially leading to serious complications.
Etymology
The term "retroperitoneal fibrosis" is derived from the Latin words 'retro' meaning 'behind', 'peritoneum' referring to the abdominal cavity lining, and 'fibrosis' indicating the formation of excess fibrous connective tissue. The condition is also named after John Kelso Ormond, who first described the disease in detail in 1948.
Symptoms
The symptoms of retroperitoneal fibrosis can vary greatly, but often include abdominal pain, back pain, and renal failure due to the compression of the ureters. Other symptoms may include fatigue, weight loss, and fever.
Causes
The exact cause of retroperitoneal fibrosis is unknown, but it is believed to be related to an autoimmune response. Certain medications, infections, and surgeries have also been associated with the condition.
Diagnosis
Diagnosis of retroperitoneal fibrosis is often made through imaging studies such as CT scan or MRI. A biopsy of the fibrous tissue may also be performed to confirm the diagnosis.
Treatment
Treatment typically involves managing the symptoms and slowing the progression of the disease. This may include the use of corticosteroids and other immunosuppressive drugs. In some cases, surgical intervention may be necessary to relieve the obstruction of the ureters.
See also
External links
- Medical encyclopedia article on Retroperitoneal fibrosis
- Wikipedia's article - Retroperitoneal fibrosis
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