SLITRK1
SLITRK1
SLITRK1 (pronounced as "slit-r-k-one") is a gene that provides instructions for making a protein that is involved in the development and function of nerve cells (neurons) in the brain.
Etymology
The term SLITRK1 is an acronym derived from the combination of two different proteins, SLIT and NTRK-like family member 1. The SLIT part of the name comes from the Drosophila gene 'slit', which is involved in the guidance of neuronal growth. The NTRK part of the name is derived from neurotrophic tyrosine kinase receptor, a type of protein that is important for neuron survival.
Function
The SLITRK1 protein is found in many areas of the brain. It is involved in the process of neurite outgrowth, which is the projection that grows out of the cell body of a neuron. This protein is also thought to play a role in maintaining proper communication between neurons in the brain.
Related Terms
- Neuron: A nerve cell that is the basic building block of the nervous system.
- Neurite outgrowth: The process of projection growth from the cell body of a neuron.
- Neurotrophic tyrosine kinase receptor: A type of protein that is important for neuron survival.
Disorders associated with SLITRK1
Mutations in the SLITRK1 gene have been associated with several neurological disorders, including Tourette syndrome, Obsessive-compulsive disorder (OCD), and Trichotillomania (hair-pulling disorder).
See Also
External links
- Medical encyclopedia article on SLITRK1
- Wikipedia's article - SLITRK1
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