Scaffolding

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Scaffolding (medicine)

Scaffolding (pronunciation: /ˈskafəldiNG/) is a term used in the field of regenerative medicine to describe the use of temporary or permanent structures to support the growth of new tissue or organs.

Etymology

The term 'scaffolding' is derived from the English word 'scaffold', which refers to a temporary structure used to support people and materials in the construction or repair of buildings and other large structures. In the context of regenerative medicine, 'scaffolding' refers to the support structure that allows for the growth of new cells and tissues.

Definition

In regenerative medicine, scaffolding is a three-dimensional structure that provides a suitable environment for cells to attach, proliferate, and differentiate. The scaffold can be made from a variety of materials, including polymers, ceramics, and composites, and can be designed to mimic the structure and function of the native extracellular matrix.

Related Terms

  • Biocompatibility: The ability of a material to perform with an appropriate host response in a specific application.
  • Biodegradable: The ability of a material to degrade over time, often through the action of living organisms.
  • Tissue engineering: The use of a combination of cells, engineering, and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological tissues.
  • Stem cell: Undifferentiated cell capable of giving rise to indefinitely more cells of the same type, and from which certain other kinds of cell arise by differentiation.

See Also

External links

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