Sequence motif
Sequence Motif
A Sequence Motif (pronounced: /ˈsiːkwəns moʊˈtif/) is a nucleotide or amino-acid sequence pattern that is widespread and has, or is conjectured to have, a biological significance. For proteins, a sequence motif is distinguished from a structural motif, a motif formed by the three-dimensional arrangement of amino acids, which may not be contiguous.
Etymology
The term "motif" comes from the French word motif, meaning "theme". In the context of genetics, it refers to a sequence of nucleotides or amino acids that is repeated or conserved, suggesting a particular function or role.
Related Terms
- Nucleotide: The basic building block of nucleic acids, such as DNA and RNA.
- Amino Acid: Organic compounds that combine to form proteins.
- Protein: Large biomolecules and macromolecules that comprise one or more long chains of amino acid residues.
- Structural Motif: A motif formed by the three-dimensional arrangement of amino acids, which may not be contiguous.
- Genetics: The study of genes, genetic variation, and heredity in living organisms.
See Also
- Conserved Sequence: A sequence of DNA or protein that has remained relatively unchanged throughout evolution.
- Active Site: The region of an enzyme where substrate molecules bind and undergo a chemical reaction.
- DNA Binding Site: A sequence of DNA where a protein such as a transcription factor binds preferentially.
External links
- Medical encyclopedia article on Sequence motif
- Wikipedia's article - Sequence motif
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