Setoperone
Setoperone
Setoperone (pronunciation: /sɛˈtɒpəroʊn/) is a radioligand and a serotonin antagonist that is used in scientific research. It is primarily used in Positron Emission Tomography (PET) scans to study the brain's serotonin system.
Etymology
The term "Setoperone" is derived from the chemical name of the compound, which is 4'-fluoro-4-phenyl-1-(2-pyrimidinyl)-1-piperazinebutyrophenone. The name is a combination of parts of the words "serotonin", "piperazine", and "phenone", which describe the compound's structure and function.
Usage
Setoperone is used as a radioligand in PET scans to study the serotonin system in the brain. It binds to the serotonin receptors, specifically the 5-HT2A receptors, allowing researchers to visualize these receptors in the brain. This can be useful in studying various mental health conditions, such as depression, anxiety, and schizophrenia, which are thought to involve abnormalities in the serotonin system.
Related Terms
- Radioligand: A type of radioactive biochemical substance that is used in imaging techniques to visualize the location of specific cells or molecules in the body.
- Serotonin Antagonist: A type of drug that blocks the action of serotonin, a neurotransmitter, in the brain.
- Positron Emission Tomography (PET): A type of imaging test that uses a radioactive substance to look for disease in the body.
- Serotonin Receptor: A type of receptor in the brain that responds to the neurotransmitter serotonin.
External links
- Medical encyclopedia article on Setoperone
- Wikipedia's article - Setoperone
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