Shine-Dalgarno sequence
Shine-Dalgarno sequence
The Shine-Dalgarno sequence (pronounced: SHYNE-dal-GAR-noh), also known as the ribosomal binding site (RBS), is a RNA sequence found in the mRNA of prokaryotic organisms. It is named after its discoverers, Australian scientists John Shine and Lynne Dalgarno.
Etymology
The term "Shine-Dalgarno sequence" is derived from the names of the two Australian scientists, John Shine and Lynne Dalgarno, who first discovered and described this sequence in 1975.
Function
The Shine-Dalgarno sequence plays a crucial role in the initiation of protein synthesis. It is located upstream of the start codon (AUG) in the mRNA and is complementary to a sequence on the small ribosomal subunit. This complementarity allows the ribosome to bind to the mRNA and correctly position it for the initiation of protein synthesis.
Related Terms
See Also
References
External links
- Medical encyclopedia article on Shine-Dalgarno sequence
- Wikipedia's article - Shine-Dalgarno sequence
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski