Solitary mastocytoma
Solitary Mastocytoma
Solitary mastocytoma (pronunciation: so-luh-ter-ee mas-toh-sy-toh-muh) is a rare form of cutaneous mastocytosis that typically presents in infancy or early childhood.
Etymology
The term "solitary mastocytoma" is derived from the Latin solus meaning "alone" or "single", and the Greek mastos meaning "breast" and -oma meaning "tumor". This refers to the single, tumor-like lesion that characterizes this condition.
Definition
A solitary mastocytoma is a benign tumor that results from an abnormal accumulation of mast cells in the skin. It is characterized by a single lesion, usually a raised, reddish-brown nodule or plaque, that can vary in size. The lesion may become itchy or swollen when rubbed or scratched, a phenomenon known as the Darier's sign.
Symptoms
Symptoms of a solitary mastocytoma can include pruritus (itching), redness, and swelling of the affected area. In some cases, systemic symptoms such as flushing, headache, abdominal pain, or anaphylaxis may occur if large amounts of histamine are released from the mast cells in the lesion.
Diagnosis
Diagnosis of a solitary mastocytoma is typically made based on the clinical presentation and confirmed by a skin biopsy. The biopsy will show an increased number of mast cells in the dermis. Additional tests, such as tryptase levels and genetic testing for KIT mutations, may be performed to rule out systemic involvement.
Treatment
Treatment for a solitary mastocytoma is usually not necessary as most lesions resolve spontaneously over time. However, if the lesion causes significant symptoms, treatment options can include topical corticosteroids, antihistamines, or mast cell stabilizers. In rare cases, surgical removal of the lesion may be considered.
Related Terms
External links
- Medical encyclopedia article on Solitary mastocytoma
- Wikipedia's article - Solitary mastocytoma
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