Splenic marginal zone lymphoma
Splenic Marginal Zone Lymphoma
Splenic Marginal Zone Lymphoma (SMZL) is a rare type of non-Hodgkin lymphoma that primarily affects the spleen.
Pronunciation
Splenic: /splɛnɪk/ Marginal: /ˈmɑːrdʒɪnəl/ Zone: /zoʊn/ Lymphoma: /lɪmˈfoʊmə/
Etymology
The term "Splenic Marginal Zone Lymphoma" is derived from its primary location and the type of cells it affects. "Splenic" refers to the spleen, "marginal zone" refers to a part of the spleen where certain types of lymphocytes (a kind of white blood cell) are found, and "lymphoma" is a general term for cancers that affect the lymphatic system.
Definition
Splenic Marginal Zone Lymphoma (SMZL) is a slow-growing B-cell lymphoma that primarily affects the spleen. It is characterized by the presence of cancerous B-cells in the marginal zone of the spleen. SMZL is a subtype of non-Hodgkin lymphoma and accounts for approximately 1% of all non-Hodgkin lymphomas.
Symptoms
Common symptoms of SMZL include splenomegaly (enlarged spleen), anemia (low red blood cell count), thrombocytopenia (low platelet count), and neutropenia (low neutrophil count). Some patients may also experience B symptoms, such as unexplained weight loss, night sweats, and fever.
Diagnosis
Diagnosis of SMZL typically involves a combination of physical examination, blood tests, imaging studies, and a biopsy of the spleen or bone marrow.
Treatment
Treatment options for SMZL depend on the stage of the disease and the patient's overall health. They may include watchful waiting, splenectomy (surgical removal of the spleen), chemotherapy, immunotherapy, or a combination of these.
Prognosis
The prognosis for patients with SMZL is generally good, with a median survival time of over 10 years. However, the disease can be difficult to treat if it has spread to other parts of the body.
Related Terms
External links
- Medical encyclopedia article on Splenic marginal zone lymphoma
- Wikipedia's article - Splenic marginal zone lymphoma
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski