Multiple system atrophy
Multiple System Atrophy
Multiple system atrophy (MSA) /ˈmʌltɪpl ˈsɪstəm ˈætrəfi/ is a rare, progressive neurodegenerative disorder characterized by a combination of symptoms that affect both the autonomic nervous system (the part of the nervous system that controls involuntary action such as blood pressure or digestion) and movement. The etymology of the term comes from the multiple systems in the body that are affected by the disease.
Symptoms
Symptoms of MSA, which can widely vary, include ataxia (problems with coordination and balance), parkinsonism (movement problems similar to those seen in Parkinson's disease), and problems with involuntary (autonomic) body functions, such as blood pressure control.
Causes
The cause of MSA is unknown. The disease tends to occur in adulthood, usually in the late 50s or early 60s. It affects both men and women.
Diagnosis
Diagnosis of MSA can be challenging due to the wide range of symptoms that can mimic other diseases. It is often confused with Parkinson's disease due to the similarity in symptoms. However, MSA tends to progress more rapidly than Parkinson's disease.
Treatment
There is currently no cure for MSA. Treatment is focused on managing symptoms. This can include medications to manage parkinsonism and ataxia, as well as lifestyle changes to manage autonomic symptoms.
Prognosis
The prognosis for individuals with MSA varies. The disease progresses gradually and can lead to severe disability. Most people with MSA live 7-10 years after symptoms first appear.
See Also
External links
- Medical encyclopedia article on Multiple system atrophy
- Wikipedia's article - Multiple system atrophy
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