Sulzberger–Garbe syndrome

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Sulzberger–Garbe syndrome (pronunciation: sʊltsˈbɛrɡər gɑːrbeɪ syndrome) is a rare, chronic skin disorder characterized by persistent, itchy, scaly patches and plaques.

Etymology

The syndrome is named after Marion Baldur Sulzberger, an American dermatologist, and Otto Garbe, a German dermatologist, who first described the condition in the mid-20th century.

Symptoms

The primary symptom of Sulzberger–Garbe syndrome is the presence of itchy, scaly patches and plaques on the skin. These can occur anywhere on the body but are most commonly found on the arms, legs, and trunk. Other symptoms may include erythema (redness of the skin), pruritus (itching), and lichenification (thickening of the skin).

Causes

The exact cause of Sulzberger–Garbe syndrome is unknown. However, it is thought to be an autoimmune disorder, where the body's immune system mistakenly attacks healthy skin cells. It may also be related to other skin conditions such as atopic dermatitis and contact dermatitis.

Diagnosis

Diagnosis of Sulzberger–Garbe syndrome is typically made based on the characteristic skin lesions. A biopsy of the affected skin may also be performed to confirm the diagnosis and rule out other skin conditions.

Treatment

Treatment for Sulzberger–Garbe syndrome primarily involves managing the symptoms. This may include the use of topical corticosteroids to reduce inflammation and itching, as well as emollients to moisturize the skin. In severe cases, immunosuppressive drugs may be used to suppress the immune system and prevent it from attacking the skin cells.

See also

External links

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