Systemic inflammation
Systemic Inflammation
Systemic inflammation is a whole-body reaction that occurs in response to an infection, injury, or chronic disease. Pronounced as /sɪˈstɛmɪk ɪnfləˈmeɪʃən/, the term is derived from the Greek word 'systema' meaning 'whole' and the Latin word 'inflammatio' meaning 'setting on fire'.
Definition
Systemic inflammation is a coordinated immune response that involves the activation of white blood cells and the release of pro-inflammatory cytokines throughout the body. This process can lead to widespread tissue damage and organ dysfunction if not properly regulated.
Causes
Systemic inflammation can be triggered by a variety of factors, including bacterial infection, viral infection, autoimmune disease, and chronic disease such as diabetes and heart disease.
Symptoms
Common symptoms of systemic inflammation include fever, fatigue, loss of appetite, and muscle weakness. In severe cases, it can lead to septic shock and multiple organ failure.
Treatment
Treatment for systemic inflammation typically involves addressing the underlying cause. This may include antibiotics for bacterial infections, antiviral drugs for viral infections, and immunosuppressive drugs for autoimmune diseases. In addition, anti-inflammatory drugs may be used to help reduce inflammation and alleviate symptoms.
Related Terms
- Inflammation
- Acute inflammation
- Chronic inflammation
- Cytokines
- White blood cells
- Immune response
- Autoimmune disease
- Septic shock
- Multiple organ failure
External links
- Medical encyclopedia article on Systemic inflammation
- Wikipedia's article - Systemic inflammation
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