TERT gene
| TERT gene | |
|---|---|
| Term | TERT gene |
| Short definition | TERT gene - A gene that makes a protein involved in maintaining the telomeres (the ends of the chromosomes). Mutations (changes) in the TERT gene have been found in some types of cancer, including melanoma, acute myeloid leukemia, breast cancer and cholangiocarcinoma (cancer that forms in the bile ducts). |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
TERT gene - A gene that makes a protein involved in maintaining the telomeres (the ends of the chromosomes). Mutations (changes) in the TERT gene have been found in some types of cancer, including melanoma, acute myeloid leukemia, breast cancer and cholangiocarcinoma (cancer that forms in the bile ducts). Mutations in the TERT gene have also been found in a rare inherited condition called dyskeratosis congenita, which causes abnormal changes in the skin and nails and white patches in the mouth. People with this condition are at increased risk of bone marrow failure (a condition in which the bone marrow does not make enough blood cells), myelodysplastic syndrome, pulmonary fibrosis (scarring of the lungs), and certain types of cancer
External links
- Medical encyclopedia article on TERT gene
- Wikipedia's article - TERT gene
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