Teriparatide
Teriparatide
Teriparatide (pronounced as teh-rih-PAR-uh-tide) is a recombinant DNA derived parathyroid hormone analogue used in the treatment of osteoporosis and other conditions that feature bone fragility.
Etymology
The term "Teriparatide" is derived from the Greek words "teri" meaning "around", "para" meaning "beside", and "tide" referring to the tides or cycles of the hormone in the body.
Usage
Teriparatide is primarily used in the treatment of osteoporosis in postmenopausal women and men at high risk for fracture and for glucocorticoid-induced osteoporosis. It is also used for men and women with osteoporosis associated with sustained systemic glucocorticoid therapy.
Mechanism of Action
Teriparatide works by stimulating new bone formation by preferential stimulation of osteoblastic activity over osteoclastic activity. This results in an overall gain in bone mineral density and bone strength, reducing the risk of fractures.
Related Terms
- Osteoporosis: A condition characterized by a decrease in the density of bone, decreasing its strength and resulting in fragile bones.
- Parathyroid hormone: A hormone produced by the parathyroid glands that regulates the serum calcium through its effects on bone, kidney, and the intestine.
- Recombinant DNA: DNA that has been formed artificially by combining constituents from different organisms.
- Osteoclast: A type of bone cell that breaks down bone tissue.
See Also
External links
- Medical encyclopedia article on Teriparatide
- Wikipedia's article - Teriparatide
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