Thrombotic thrombocytopenic purpura

Thrombotic Thrombocytopenic Purpura

Thrombotic thrombocytopenic purpura (TTP) is a rare blood disorder characterized by clotting in small blood vessels of the body (thromboses), resulting in a low platelet count (thrombocytopenia). Pronounced as throm-BO-tik throm-bo-cy-toe-PEN-ik PUR-pu-ra.

Etymology

The term "Thrombotic thrombocytopenic purpura" is derived from the Greek words "thrombos" meaning clot, "kytos" meaning hollow vessel, "penia" meaning poverty, and "purpura" meaning purple, referring to the color of the skin lesions.

Symptoms

The symptoms of TTP may include fatigue, purpura, thrombocytopenia, hemolytic anemia, and neurological abnormalities.

Causes

TTP can be caused by various conditions including pregnancy, cancer, HIV, certain medications, and infections. It can also be hereditary.

Diagnosis

Diagnosis of TTP typically involves blood tests, including a complete blood count (CBC), and sometimes a bone marrow biopsy.

Treatment

Treatment for TTP often involves plasma exchange (plasmapheresis) and immunosuppressive drugs.

Related Terms

• Thrombosis
• Thrombocytopenia
• Purpura
• Plasmapheresis
• Immunosuppressive drugs

External links

• Medical encyclopedia article on Thrombotic thrombocytopenic purpura
• Wikipedia's article - Thrombotic thrombocytopenic purpura

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