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Thymidylate synthase inhibitor

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Thymidylate synthase inhibitor - any substance that inhibits thymidylate synthase, an enzyme that catalyzes the conversion of uridine monophosphate to thymidine monophosphate, the rate-limiting step in de novo production of dtmp. Inhibition of thymidylate synthase causes inhibition of dna synthesis and cell proloferation.

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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Thymidylate synthase inhibitor for any updates.


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