Treatment-resistant depression
Treatment-resistant depression (pronounced: tree-tuh-ment re-zis-tuhnt de-pre-shun) is a term used in clinical psychiatry to describe cases of major depressive disorder (MDD) that do not respond adequately to appropriate courses of at least two antidepressants.
Etymology
The term "treatment-resistant depression" is a modern term in psychiatry. The term "resistant" comes from the Latin resistere, meaning "to withstand". The term "depression" comes from the Latin deprimere, meaning "to press down".
Definition
Treatment-resistant depression is defined as the lack of a clinical response after adequate treatment with appropriate medications. The American Psychiatric Association defines it as a failure of two treatment trials.
Related Terms
- Major depressive disorder: A mental health disorder characterized by persistently depressed mood or loss of interest in activities, causing significant impairment in daily life.
- Antidepressant: Medications designed to reduce or prevent the symptoms of depression.
- Psychotherapy: A general term for treating mental health problems by talking with a psychiatrist, psychologist or other mental health provider.
- Electroconvulsive therapy: A procedure, done under general anesthesia, in which small electric currents are passed through the brain, intentionally triggering a brief seizure.
- Transcranial magnetic stimulation: A noninvasive procedure that uses magnetic fields to stimulate nerve cells in the brain to improve symptoms of depression.
Treatment
Treatment-resistant depression can be challenging to treat. However, there are several strategies that can be used, including optimizing medication, switching antidepressants, combining medications, and considering non-drug therapies such as psychotherapy, electroconvulsive therapy, or transcranial magnetic stimulation.
See Also
External links
- Medical encyclopedia article on Treatment-resistant depression
- Wikipedia's article - Treatment-resistant depression
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