Triazolam

From WikiMD

Information about Triazolam

Triazolam is an orally available benzodiazepine used predominantly for therapy of insomnia

Liver safety of Triazolam

As with most benzodiazepines, triazolam therapy has not been associated with serum aminotransferase or alkaline phosphatase elevations, and clinically apparent liver injury from triazolam has been reported but is very rare.

Mechanism of action of Triazolam

Triazolam (trye az" oh lam) is a benzodiazepine that is widely used as a sleeping aid in the therapy of insomnia.  The soporific activity of the benzodiazepines is mediated by their ability to enhance gamma-aminobutyric acid (GABA) mediated inhibition of synaptic transmission through binding to the GABA A receptor.  Triazolam was approved in the United States in 1982 and was formerly the most common prescription sleeping pill used in the United States.  Concerns over its safety led to its withdrawal from use in the UK, and the availability of other potent, shorter acting sleeping pills has caused its decrease in general use in the United States. 

Clinical use of Triazolam

Current indications are for the short term management of insomnia

Dosage and administration for Triazolam

Triazolam is available in multiple generic forms and under the brand name Halcion in tablets of 0.125 and 0.25 mg.  The recommended initial dose for adults is 0.125 mg immediately before bedtime, increasing to 0.25 as needed; rarely, higher doses are used. 

Side effects of Triazolam

The most common side effects of triazolam are dose related and include daytime drowsiness, lethargy, ataxia, dysarthria and dizziness.  Tolerance develops to these side effects, but tolerance may also develop to the soporific effects.  Triazolam is classified as a schedule IV controlled substance, indicating that it has a potential for physical and psychological dependence and abuse.

Benzodiazipines

Anticonvulsants Drugs

Drug class for Triazolam

Anticonvulsants, and Benzodiazepines]
The article on Triazolam is a stub. YOU can help Wikimd by expanding it!

Medication resources

Learn more


edit 

About WikiMD

About us: WikiMD is a free medical encyclopedia and wellnesspedia moderated by medical professionals.

Our mission: Provide up to date physician reviewed health, nutrition and wellness information for free in over 100 languages.

Join us: This article is a stub. Help improve Triazolam or others. Do not trust amateurs with your life! Join us in this effort!. Paid editors welcome.

Pubmed.png Uptodate.png Wikipedia Reddit YouTube videos
W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's insurance Weight loss program can HELP*

Quick links: Medicine Portal | Encyclopedia‏‎‏‎ | Gray's Anatomy‏‎ | Topics‏‎ |‏‎ Diseases‏‎ | Drugs | Wellness | Obesity‏‎ | Metabolic syndrome | Weight loss*
Disclaimer: The entire contents of WIKIMD.ORG are for informational purposes only and do not render medical advice or professional services. If you have a medical emergency, you should CALL 911 immediately! Given the nature of the wiki, the information provided may not be accurate, misleading and or incorrect. Use the information on this wiki at your own risk! See full Disclaimer.
Link to this page: <a href="http://www.wikimd.org/wiki/Triazolam">Triazolam</a>

  • Individual results may vary for weight loss from our sponsors.