Tropomyosin receptor kinase protein family
Tropomyosin receptor kinase protein family | |
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Term | Tropomyosin receptor kinase protein family |
Short definition | tropomyosin receptor kinase protein family - (pronounced) (TROH-poh-MY-oh-sin reh-SEP-ter KY-nays PROH-teen FA-mih-lee) family of proteins found on nerve cells. They are involved in cell signaling pathways that control cell growth, cell maturation, and cell survival. |
Type | Cancer terms |
Specialty | Oncology |
Language | English |
Source | NCI |
Comments |
tropomyosin receptor kinase protein family - (pronounced) (TROH-poh-MY-oh-sin reh-SEP-ter KY-nays PROH-teen FA-mih-lee) family of proteins found on nerve cells. They are involved in cell signaling pathways that control cell growth, cell maturation, and cell survival. The genes that make the tropomyosin receptor kinase proteins can have mutations (changes) that lead to the formation of abnormal tropomyosin receptor kinase proteins. These abnormal proteins can be overactive or found in higher than normal amounts on some types of cancer cells, which can cause cancer cells to grow. Drugs that block tropomyosin receptor kinase proteins are used in the treatment of some types of cancer. Tropomyosin receptor kinase proteins are receptor tyrosine kinases. Also referred to as the TRK family of proteins
External links
- Medical encyclopedia article on Tropomyosin receptor kinase protein family
- Wikipedia's article - Tropomyosin receptor kinase protein family
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