Typical antipsychotics

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Typical Antipsychotics

Typical antipsychotics (pronunciation: /ˈtɪpɪkəl ˌæntɪsaɪˈkɒtɪks/), also known as first-generation antipsychotics or FGAs, are a class of antipsychotic drugs primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. They are also used in the treatment of other types of mental disorders.

Etymology

The term "typical antipsychotics" is derived from their difference from the newer and atypical antipsychotics, which are less likely to cause certain side effects. The term "first-generation" refers to the first wave of such drugs that were developed.

Pharmacology

Typical antipsychotics are dopamine antagonist, and work by blocking dopamine receptors in the brain. This helps to balance the levels of dopamine, which can reduce symptoms of psychosis.

Side Effects

Common side effects of typical antipsychotics include drowsiness, dizziness, and restlessness. More serious side effects may include tardive dyskinesia and neuroleptic malignant syndrome.

Related Terms

  • Atypical antipsychotics: A newer class of antipsychotic drugs that are less likely to cause certain side effects.
  • Psychosis: A mental disorder characterized by a disconnection from reality.
  • Schizophrenia: A long-term mental disorder involving a breakdown in the relation between thought, emotion, and behavior.
  • Bipolar disorder: A disorder associated with episodes of mood swings ranging from depressive lows to manic highs.

See Also

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