Uremic frost
Uremic Frost
Uremic frost (pronounced: yoo-REE-mik frost) is a rare dermatological condition that occurs in severe cases of kidney failure. The term "uremic" is derived from the Greek words "ouron" meaning urine and "haima" meaning blood, and "frost" refers to the appearance of the condition on the skin.
Definition
Uremic frost is characterized by the crystallization of urea and urea derivatives on the skin due to high levels of urea in the blood (a condition known as uremia). This occurs when the kidneys are unable to properly filter waste products from the blood, leading to their accumulation and subsequent excretion through sweat. When the sweat evaporates, it leaves behind a residue of urea crystals, giving the skin a frosted or powdered appearance.
Symptoms
The primary symptom of uremic frost is a white or pale yellow crystalline deposit on the skin, particularly in areas of heavy perspiration such as the forehead, armpits, and groin. Other symptoms may include itching, dry skin, and an unpleasant odor. Uremic frost is often accompanied by other symptoms of kidney failure, such as fatigue, nausea, vomiting, and a decreased ability to think clearly.
Causes
Uremic frost is caused by severe kidney failure, which can result from a variety of conditions including chronic kidney disease, acute kidney injury, and certain genetic disorders such as polycystic kidney disease. Other potential causes include long-term use of certain medications, high blood pressure, and diabetes.
Treatment
Treatment for uremic frost primarily involves addressing the underlying kidney failure. This may include dialysis, a procedure that artificially filters waste products from the blood, or kidney transplantation. Topical treatments such as emollients and urea creams may also be used to help manage the skin symptoms.
See Also
External links
- Medical encyclopedia article on Uremic frost
- Wikipedia's article - Uremic frost
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