Uricosuric agents
Uricosuric Agents
Uricosuric agents (pronounced: yoo-rih-ko-SUR-ik AY-jents) are a class of drugs that increase the excretion of uric acid in the urine, thus reducing the concentration of uric acid in the blood. They are primarily used in the treatment of gout, a condition characterized by high levels of uric acid in the blood.
Etymology
The term "uricosuric" is derived from the Latin words "urica" meaning "uric acid" and "surere" meaning "to cast out". The term "agent" is derived from the Latin word "agens" meaning "a thing that produces or causes".
Mechanism of Action
Uricosuric agents work by inhibiting the reabsorption of uric acid in the kidney. This leads to an increase in the excretion of uric acid in the urine, thereby reducing the concentration of uric acid in the blood.
Examples
Examples of uricosuric agents include Probenecid, Sulfinpyrazone, and Benzbromarone. These drugs are often used in combination with other medications to treat gout.
Side Effects
Common side effects of uricosuric agents include nausea, vomiting, and diarrhea. In rare cases, these drugs can cause serious side effects such as kidney stones and anemia.
Related Terms
- Uric acid
- Gout
- Kidney
- Probenecid
- Sulfinpyrazone
- Benzbromarone
- Nausea
- Vomiting
- Diarrhea
- Kidney stones
- Anemia
External links
- Medical encyclopedia article on Uricosuric agents
- Wikipedia's article - Uricosuric agents
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