Ussing chamber

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Ussing Chamber

The Ussing Chamber (pronounced: "oo-sing chamber") is a device used in the field of physiology and pharmacology to measure the transport of various substances and ions across epithelial tissues. It was named after the Danish scientist Hans Ussing, who first introduced the device in the 1950s.

Etymology

The Ussing Chamber is named after Hans Ussing, a Danish scientist known for his work in the field of ion transport across biological membranes. Ussing and his colleagues developed the device to study the transport of ions across the frog skin.

Function

The Ussing Chamber is designed to hold a thin layer of epithelial tissue between two halves of the chamber. Each half of the chamber is filled with a solution, and the transport of ions or other substances across the tissue can be measured by changes in the electrical potential difference, resistance, and short-circuit current.

Related Terms

  • Epithelial Tissue: A type of tissue that lines the outer surfaces of organs and blood vessels, as well as the inner surfaces of cavities in many internal organs.
  • Ion Transport: The movement of ions across a membrane, often against a concentration gradient, through active or passive transport.
  • Pharmacology: The branch of medicine concerned with the uses, effects, and modes of action of drugs.
  • Physiology: The scientific study of the functions and mechanisms in a living system.

See Also

External links

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