Valproate pivoxil
Valproate Pivoxil
Valproate pivoxil (pronunciation: val-PRO-ate pi-VOX-il) is a prodrug of valproic acid, a medication primarily used to treat epilepsy and bipolar disorder and to prevent migraine headaches.
Etymology
The term "valproate" is derived from the chemical compound valproic acid, which was first synthesized in 1882 by Beverly Burton. The term "pivoxil" is a common suffix used in pharmaceutical nomenclature to denote a pivaloyloxymethyl ester prodrug.
Pharmacology
Valproate pivoxil is metabolized in the stomach to produce valproic acid. The conversion process allows for a more controlled release of the active drug, reducing the potential for side effects and improving the overall effectiveness of the medication.
Usage
Valproate pivoxil is used in the treatment of various types of seizures in epilepsy, in the prevention of migraines, and in the management of bipolar disorder. It is also used off-label for other conditions, such as neuropathic pain and aggression in dementia.
Side Effects
Common side effects of valproate pivoxil include nausea, vomiting, dizziness, and hair loss. More serious side effects can include liver problems, pancreatitis, and an increased risk of suicidal thoughts and behaviors.
Related Terms
External links
- Medical encyclopedia article on Valproate pivoxil
- Wikipedia's article - Valproate pivoxil
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