W8MD Diet | COVID-19 portal | Vitamin D | Vaccine | Keto

WikiMD is the world's largest medical encyclopedia with
14,007 pages, 4,159,090 edits & 43,392,504 views.

Free unbiased diet, health and wellness info!

Valrubicin

From WikiMD's free health, diet & wellness encyclopedia
Jump to navigation Jump to search

Valrubicin (val-ROO-bih-sin)A drug used to treat bladder carcinoma in situ that did not get better after treatment with bacillus Calmette-Guerin (BCG). It is used in patients who cannot have surgery right away to remove all or part of the bladder. Valrubicin is given as a solution through a catheter that is placed into the bladder. It blocks a certain enzyme needed for cell division and DNA repair, and it may kill cancer cells. Valrubicin is a type of anthracycline antibiotic and a type of topoisomerase inhibitor. Also called AD 32 and Valstar.


Information about Valrubicin

Valrubicin is a synthetic analogue of doxorubicin that is used to treat refractory urinary bladder cancer.

Clinical use of Valrubicin

Valrubicin has been shown to induce clinical remissions in 18% to 30% of patients. It was approved as a therapy of bladder cancer in the United States 1998, was removed in 2002 because of manufacturing issues, but reintroduced in 2009.

Dosage and administration for Valrubicin

Valrubicin is available only for intravesicular use in 5 mL single dose vials of 200 mg under the brand name Valstar. The recommended dose is 800 mg instilled in the bladder once weekly for 6 weeks.

Side effects of Valrubicin

Common side effects include bladder pain and irritation, urgency and dysuria. Systemic absorption is minimal and systemic side effects are uncommon.

Alphabetic list of antineoplastic agents - 0-9 - A1 - A2 - A3 - A4 - A5 -A6 - B - C - D - E - F - G - H - I - JK - L - M - NO - PQ - R - S - T - UVW - XYZ

Cost and Coupons - Valrubicin

Reviews for Valrubicin

Learn more about Valrubicin

Latest research - Valrubicin

PubMed
Clinical trials

External links

Wikipedia
Medicine icon
Medicine icon

This WikiMD article Valrubicin is a stub. If you are familiar with the topic Valrubicin, you can help us. Paid editors welcome!

 

Valrubicin is part of WikiMD's free ^articles!

^Valrubicin (article) is provided for informational purposes only. No expressed or implied warranties as to the validity of content.
WikiMD is not a substitute for professional advice. By accessing and using WikiMD you agree to the terms of use.
Templates etc. when imported from Wikipedia, are licensed under CC BY-SA 3.0. See full disclaimers.
W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's physician weight loss program can HELP. Tele medicine available