WikiMD is the world's largest medical encyclopedia with
13,590 pages, 4,139,107 edits & 37,811,477 views.
Valrubicin
Valrubicin (val-ROO-bih-sin)A drug used to treat bladder carcinoma in situ that did not get better after treatment with bacillus Calmette-Guerin (BCG). It is used in patients who cannot have surgery right away to remove all or part of the bladder. Valrubicin is given as a solution through a catheter that is placed into the bladder. It blocks a certain enzyme needed for cell division and DNA repair, and it may kill cancer cells. Valrubicin is a type of anthracycline antibiotic and a type of topoisomerase inhibitor. Also called AD 32 and Valstar.
Information about Valrubicin
Valrubicin is a synthetic analogue of doxorubicin that is used to treat refractory urinary bladder cancer.
Clinical use of Valrubicin
Valrubicin has been shown to induce clinical remissions in 18% to 30% of patients. It was approved as a therapy of bladder cancer in the United States 1998, was removed in 2002 because of manufacturing issues, but reintroduced in 2009.
Dosage and administration for Valrubicin
Valrubicin is available only for intravesicular use in 5 mL single dose vials of 200 mg under the brand name Valstar. The recommended dose is 800 mg instilled in the bladder once weekly for 6 weeks.
Side effects of Valrubicin
Common side effects include bladder pain and irritation, urgency and dysuria. Systemic absorption is minimal and systemic side effects are uncommon.
Alphabetic list of antineoplastic agents - 0-9 - A1 - A2 - A3 - A4 - A5 -A6 - B - C - D - E - F - G - H - I - JK - L - M - NO - PQ - R - S - T - UVW - XYZ
Cost and Coupons - Valrubicin
- GoodRx compare cost & coupons for Valrubicin
- Find the lowest cost of Valrubicin
- Search for Coupons for Valrubicin
Reviews for Valrubicin
Learn more about Valrubicin
- Dailymed label info
- Scientific articles
- Drug portal Valrubicin
- toxicity info on Valrubicin
- FDA Valrubicin
Latest research - Valrubicin
External links
This WikiMD article Valrubicin is a stub. If you are familiar with the topic Valrubicin, you can help us. Paid editors welcome!
Valrubicin is part of WikiMD's free ^articles!
WikiMD is not a substitute for professional advice. By accessing and using WikiMD you agree to the terms of use.
Templates etc. when imported from Wikipedia, are licensed under CC BY-SA 3.0. See full disclaimers.
 Ad. Tired of being overweight?. W8MD's physician weight loss program can HELP. Tele medicine available |
