WHIM syndrome

From WikiMD.org
Jump to navigation Jump to search

WHIM Syndrome

WHIM syndrome (pronounced /wɪm/), is a rare, autosomal dominant immunodeficiency disorder. The name "WHIM" is an acronym for the main clinical features of the syndrome: Warts, Hypogammaglobulinemia, Infections, and Myelokathexis.

Etymology

The term "WHIM" is an acronym derived from the initial letters of the main clinical features of the syndrome: Warts, Hypogammaglobulinemia, Infections, and Myelokathexis. The syndrome was first described in 1964 by Zuelzer and colleagues, but the term "WHIM syndrome" was not coined until 1990.

Pronunciation

WHIM syndrome is pronounced as /wɪm/ syndrome.

Related Terms

  • Warts: Small, benign growths caused by a viral infection of the skin or mucous membrane. In WHIM syndrome, patients often have extensive warts, especially on the hands and feet.
  • Hypogammaglobulinemia: A condition characterized by lower-than-normal levels of immunoglobulins, the proteins that function as antibodies. This leads to an increased susceptibility to infections.
  • Infections: In WHIM syndrome, patients are more susceptible to bacterial and viral infections due to their compromised immune system.
  • Myelokathexis: A condition characterized by the retention of neutrophils in the bone marrow, leading to neutropenia (low neutrophil count) in the blood. This is a unique feature of WHIM syndrome.

See Also

External links

Esculaap.svg

This WikiMD dictionary article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski