Wells syndrome

Wells Syndrome

Wells syndrome (pronounced: /wɛlz ˈsɪndroʊm/), also known as eosinophilic cellulitis, is a rare skin condition first described by George Crichton Wells in 1971.

Etymology

The term "Wells syndrome" is derived from the name of the British dermatologist, George Crichton Wells, who first identified and described the condition. The term "eosinophilic cellulitis" refers to the characteristic presence of eosinophils (a type of white blood cell) in the skin lesions associated with the condition.

Definition

Wells syndrome is a recurrent granulomatous dermatitis characterized by inflammatory, painful, and pruritic skin lesions that typically resolve without scarring. The condition is associated with an increased number of eosinophils in the affected skin and occasionally in the peripheral blood.

Symptoms

The primary symptom of Wells syndrome is the appearance of skin lesions, which can vary in size and shape. These lesions are typically erythematous, edematous, and may resemble cellulitis. Other symptoms may include itching, burning sensation, and tenderness at the site of the lesion. Systemic symptoms such as fever and malaise may also occur.

Diagnosis

Diagnosis of Wells syndrome is primarily based on clinical findings and histopathological examination of a skin biopsy, which typically shows a dense infiltrate of eosinophils in the dermis.

Treatment

Treatment for Wells syndrome primarily involves the use of corticosteroids to reduce inflammation and control symptoms. Other treatments may include antihistamines to manage itching, and in severe cases, immunosuppressive drugs may be used.

Related Terms

• Eosinophilia
• Dermatitis
• Cellulitis
• Corticosteroids
• Antihistamines
• Immunosuppressive drugs

External links

• Medical encyclopedia article on Wells syndrome
• Wikipedia's article - Wells syndrome

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