Wernicke Korsakoff syndrome
Wernicke-Korsakoff Syndrome
Wernicke-Korsakoff Syndrome (pronounced: VERN-ih-kee kor-sa-KOFF) is a neurological disorder characterized by severe memory loss, confusion, and difficulty with coordination. It is primarily caused by a deficiency in the vitamin thiamine (vitamin B1).
Etymology
The syndrome is named after two physicians, Carl Wernicke and Sergei Korsakoff, who independently described the condition in the late 19th century. Wernicke, a German neurologist, first identified the acute phase of the disorder, which is now known as Wernicke's encephalopathy. Korsakoff, a Russian psychiatrist, later described the chronic phase, now known as Korsakoff's psychosis.
Symptoms
The symptoms of Wernicke-Korsakoff Syndrome can be divided into two stages. The first stage, Wernicke's encephalopathy, is characterized by mental confusion, eye movement disorders, and unsteady coordination. The second stage, Korsakoff's psychosis, is characterized by severe memory loss and the inability to form new memories.
Causes
Wernicke-Korsakoff Syndrome is primarily caused by a deficiency in thiamine. This deficiency is most commonly seen in individuals with chronic alcoholism, but it can also occur as a result of malnutrition, prolonged fasting, or the inability to absorb nutrients due to conditions such as gastric bypass surgery.
Treatment
Treatment for Wernicke-Korsakoff Syndrome involves replacing the deficient thiamine, often through high-dose supplements. In some cases, dietary changes or treatment for alcoholism may also be necessary.
Related Terms
External links
- Medical encyclopedia article on Wernicke Korsakoff syndrome
- Wikipedia's article - Wernicke Korsakoff syndrome
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