Xgeva

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Xgeva
TermXgeva
Short definitionXgeva - (pronounced) (ex-JEE-vuh) drug that contains the active ingredient denosumab and is used to prevent or treat certain bone problems. Xgeva is used to prevent bone problems caused by multiple myeloma, or solid tumors that have spread to the bone. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


Xgeva - (pronounced) (ex-JEE-vuh) drug that contains the active ingredient denosumab and is used to prevent or treat certain bone problems. Xgeva is used to prevent bone problems caused by multiple myeloma, or solid tumors that have spread to the bone. It is also used in certain patients to treat giant cell tumors of the bone that cannot be surgically removed and to treat hypercalcaemia related to cancer that has not improved after treatment with bisphosphonates. Xgeva attaches to a protein called RANKL, which prevents RANKL from attaching to another protein called RANK on the surface of certain bone cells, including bone cancer cells. This can help prevent bone loss and cancer cell growth. Xgeva can also prevent the loss of calcium from the bones. It's a type of monoclonal antibody

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