Zofenoprilat

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Zofenoprilat (pronunciation: zo-fen-o-pril-at) is the active metabolite of Zofenopril, an Angiotensin Converting Enzyme (ACE) inhibitor used in the treatment of hypertension and heart failure.

Etymology

The term "Zofenoprilat" is derived from its parent drug, Zofenopril. The suffix "-at" is commonly used to denote active metabolites of a drug.

Pharmacology

Zofenoprilat inhibits the Angiotensin Converting Enzyme, which is involved in the conversion of angiotensin I to angiotensin II. By inhibiting this enzyme, Zofenoprilat reduces the levels of angiotensin II, a potent vasoconstrictor, leading to decreased blood pressure.

Clinical Use

Zofenoprilat, through its parent drug Zofenopril, is used in the treatment of conditions such as hypertension and heart failure. It may also be used in patients with myocardial infarction.

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