Osmotic controlled-release oral delivery system

OROS (Osmotic [Controlled] Release Oral [Delivery] System) is a controlled release oral drug delivery system in the form of a tablet. The tablet has a rigid water-permeable jacket with one or more laser drilled small holes. As the tablet passes through the body, the osmotic pressure of water entering the tablet pushes the active drug through the opening in the tablet.

OROS is a trademarked name owned by Alza Corporation. OROS medications include:
 * Adalat OROS (nifedipine)
 * Alpress LP (prazosin)
 * Cardura XL (doxazosin)
 * Concerta (methylphenidate)
 * Covera-HS (verapamil)
 * Ditropan XL / Lyrinel XL (oxybutynin)
 * DynaCirc CR (isradipine)
 * Glucotrol XL (glipizide)
 * Invega (paliperidone)
 * Jurnista / Exalgo (hydromorphone)
 * Procardia XL (nifedipine)
 * Volmax (salbutamol)

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