Polybrene

Polybrene (hexadimethrine bromide) is a cationic polymer used to increase the efficiency of infection of certain cells with a retrovirus in cell culture. Polybrene acts by neutralizing the charge repulsion between virions and sialic acid on the cell surface. It has other uses, including a role in protein sequencing.

The chemical name for Polybrene is 1,5-dimethyl-1,5-diazaundecamethylene polymethobromide, hexadimethrine bromide.