Mixing of stimulants and depressants

Mixing of stimulants and depressants can have unpredictable and/or dangerous results. Certain combinations can produce coma and death. The mixing of energy drinks with ethanol reduces one’s ability to accurately assess one’s own intoxication levels and reduces objective self measures of impairment. Mixing stimulants with heroin, a combination known as a speedball, is said to produce an unusually intense high. Mixing cocaine use with alcohol or other drugs increases the chances of an overdose. Alcohol is sometimes mixed with coffee.