Casomorphin

Casomorphins are peptides, i.e., protein fragments, derived from the digestion of milk protein casein.

There is no evidence that these peptides have any significance in human health.

Health
Digestive enzymes can break casein down into peptides that have some biological activity in cells and in laboratory animals. They have not been shown to have any effect on humans and they not been proven to be formed in the human digestive system. Although research has shown high rates of use of complementary and alternative therapies for children with autism, including gluten and/or casein exclusion diets, there was a lack of evidence that these diets had any effect.

β-Casomorphin 1-3

 * Structure: H-Tyr-Pro-Phe-OH
 * Chemical formula: C23H27N3O5
 * Molecular weight: 425.48 g/mol

Bovine β-casomorphin 1-4

 * Structure: H-Tyr-Pro-Phe-Pro-OH
 * Chemical formula: C 28 H 35 N 4 O 6
 * Molecular weight: 522.61 g/mol

Bovine β-casomorphin 1-4, amide
Also known as morphiceptin
 * Structure: H-Tyr-Pro-Phe-Pro-NH2
 * Chemical formula: C28H35N5O5
 * Molecular weight: 521.6 g/mol

Bovine β-casomorphin 5

 * Structure: H-Tyr-Pro-Phe-Pro-Gly-OH
 * Chemical formula: C30H37N5O7
 * Molecular weight: 594.66 g/mol

Bovine β-casomorphin 7

 * Structure: H-Tyr-Pro-Phe-Pro-Gly-Pro-Ile-OH
 * Chemical formula: C41H55N7O9
 * Molecular weight: 789.9 g/mol

Bovine β-casomorphin 8
(Note: There is also a form of bovine β-Casomorphin 8 that has histidine instead of proline in position 8, depending on whether it is derived from A1 or A2 beta-casein.)
 * Structure: H-Tyr-Pro-Phe-Pro-Gly-Pro-Ile-Pro-OH
 * Chemical formula: C46H62N8O10
 * Molecular weight: 887.00 g/mol