10-Deacetylbaccatin

10-Deacetylbaccatins are a series of closely related natural organic compounds isolated from the Pacific yew tree (Taxus brevifolia) and related species. 10-Deacetylbaccatin III is a precursor to the anti-cancer drug docetaxel (Taxotere).

10-deacetylbaccatin III 10-O-acetyltransferase converts 10-Deacetylbaccatin to baccatin III. (acetyl-CoA + 10-deacetylbaccatin III $$\rightleftharpoons$$ CoA + baccatin III)