Pendetide

Pendetide (GYK-DTPA) is a chelating agent. It consists of pentetic acid (DTPA) linked to the tripeptide glycine (G) – L -tyrosine (Y) – L -lysine (K).

Use
The following monoclonal antibodies are linked to pendetide to chelate a radionuclide, indium-111. The antibodies selectively bind to certain tumour cells, and the radioactivity is then used for imaging of the tumours.
 * Indium (111In) capromab pendetide (prostate cancer)
 * Indium (111In) satumomab pendetide (other cancer types)