Amitriptyline

From WikiMD
Jump to navigation Jump to search
Other languages:
English

Information about Amitriptyline

Amitriptyline is a tricyclic antidepressant that is widely used in the therapy of depression.

Liver safety of Amitriptyline

Amitriptyline can cause mild and transient serum enzyme elevations and is rare cause of clinically apparent acute cholestatic liver injury.

Mechanism of action of Amitriptyline

Amitriptyline (am" i trip' ti leen) is a tricyclic antidepressant which is believed to act by inhibition of serotonin and norepinephrine reuptake within synaptic clefts in the central nervous system, thus increasing brain levels of these neurotransmitters.

Clinical use of Amitriptyline

Amitriptyline is indicated for therapy of depression and was approved for this indication in the United States in 1961, and is still widely used, with more than 10 million prescriptions for amitriptyline being filled yearly. Amitriptyline is also used for anorexia and bulimia and for adjunctive treatment of neurogenic pain.

Dosage and administration for Amitriptyline

Amitriptyline is available in generic forms and under the brand name of Elavil in 10, 25, 50, 75, 100 and 150 mg tablets. The typical recommended dose for depression in adults is 75 to 100 mg daily in divided doses, increasing gradually to a maximum of 300 mg daily. Amitriptyline can also be given as a single nighttime dose of 50 to 150 mg.

Side effects of Amitriptyline

Common side effects include dizziness, headache, drowsiness, restlessness, confusion, gastrointestinal upset, increased appetite, weight gain, blurred vision, dry mouth and urinary retention.

The following are antidepressant subclasses and drugs

MAO Inhibitors Isocarboxazid, Phenelzine, Tranylcypromine

SNRIs Duloxetine, Levomilnacipran, Venlafaxine

SSRIs Citalopram, Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline, Vilazodone, Vortioxetine

Tricyclics Amitriptyline, Amoxapine, Clomipramine, Desipramine, Doxepin, Imipramine, Nortriptyline, Protriptyline, Trimipramine

Miscellaneous Bupropion, Flibanserin, Mirtazapine, Nefazodone, Trazodone


Cost and Coupons - Amitriptyline

Reviews for Amitriptyline


Wellness that matters!

Articles on Amitriptyline

This article is a stub. YOU can help Wikimd by expanding it!

Learn more about Amitriptyline

Drug classes


Photofacial-before-and-after

WikiMD resources for Amitriptyline

The following chart shows the WikiMD resources in a 360 degree point of view bringing together resources from scientific articles to social media. Social Media on Amitriptyline

Reddit
Quora.png
Pins
Instagram
YouTube videos
Flickr
Bing.png

Articles

Most recent articles for Amitriptyline:

Media

Media articles for Amitriptyline:

Books and news:

Commentary:

Scientific articles

Evidence based medicine for Amitriptyline:

Clinical trials for Amitriptyline:

Resources

Patient resources for Amitriptyline:

W8MD A-Z health topics: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U |V | W | X | Y | Z

W8MD logo

Ad. Tired of being overweight?. W8MD's insurance weight loss can HELP*

Lose weight King of Prussia, PA | Lose weight NYC | Lose weight NJ | Lose weight Philadelphia | Advertise
Other languages:
English

Disclaimer: The entire contents of WIKIMD.ORG are for informational purposes only and do not render medical advice or professional services. If you have a medical emergency, you should CALL 911 immediately! Given the nature of the wiki, the information provided may not be accurate, misleading and or incorrect. Use the information on this wiki at your own risk! See full Disclaimer. * Individual results may vary for weight loss from our sponsors.

Our sponsors WikiMD is supported by W8MD weight loss, sleep and medical aesthetic centers.