Amitriptyline

From WikiMD free wellness and medical encyclopedia
Jump to: navigation, search

Information about Amitriptyline

Amitriptyline is a tricyclic antidepressant that is widely used in the therapy of depression.

Liver safety of Amitriptyline

Amitriptyline can cause mild and transient serum enzyme elevations and is rare cause of clinically apparent acute cholestatic liver injury.

Mechanism of action of Amitriptyline

Amitriptyline (am" i trip' ti leen) is a tricyclic antidepressant which is believed to act by inhibition of serotonin and norepinephrine reuptake within synaptic clefts in the central nervous system, thus increasing brain levels of these neurotransmitters.

Clinical use of Amitriptyline

Amitriptyline is indicated for therapy of depression and was approved for this indication in the United States in 1961, and is still widely used, with more than 10 million prescriptions for amitriptyline being filled yearly. Amitriptyline is also used for anorexia and bulimia and for adjunctive treatment of neurogenic pain.

Dosage and administration for Amitriptyline

Amitriptyline is available in generic forms and under the brand name of Elavil in 10, 25, 50, 75, 100 and 150 mg tablets. The typical recommended dose for depression in adults is 75 to 100 mg daily in divided doses, increasing gradually to a maximum of 300 mg daily. Amitriptyline can also be given as a single nighttime dose of 50 to 150 mg.

Side effects of Amitriptyline

Common side effects include dizziness, headache, drowsiness, restlessness, confusion, gastrointestinal upset, increased appetite, weight gain, blurred vision, dry mouth and urinary retention.

The following are antidepressant subclasses and drugs

MAO Inhibitors Isocarboxazid, Phenelzine, Tranylcypromine

SNRIs Duloxetine, Levomilnacipran, Venlafaxine

SSRIs Citalopram, Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline, Vilazodone, Vortioxetine

Tricyclics Amitriptyline, Amoxapine, Clomipramine, Desipramine, Doxepin, Imipramine, Nortriptyline, Protriptyline, Trimipramine

Miscellaneous Bupropion, Flibanserin, Mirtazapine, Nefazodone, Trazodone


Cost and Coupons - Amitriptyline

Reviews for Amitriptyline



Articles on Amitriptyline

This article is a stub. YOU can help Wikimd by expanding it!

Learn more about Amitriptyline

WikiMD is a free medical encyclopedia and wellnesspedia moderated by medical professionals and is a reliable source of information on a wide range of health, weight loss and wellness related topics.


Drug classes

 

WikiMD Resources 360 - Amitriptyline
360.png
Scientific articles to social media

Articles

Policies / Guidelines
  1. Most recent articles
  2. Most cited articles
  3. Review articles
  4. in N Eng J Med, Lancet, BMJ
  1. US National Guidelines Clearinghouse
  2. NICE Guidance
  3. FDA on Amitriptyline
  4. CDC on Amitriptyline

Media articles

Patient Resources / Community
  1. Powerpoint Slides
  2. Images
  3. Podcasts & MP3s
  4. Videos
  1. Patient Resources
  2. Discussion groups
  3. Patient Handouts
  4. Doctors for Amitriptyline

Evidence Based Medicine

Healthcare Provider Resources
  1. Cochrane Collaboration
  2. Bandolier
  3. TRIP
  4. Edidence Based Medicine
  1. Condition/symptom
  2. Causes & Risk Factors
  3. Tests/studies
  4. Treatment

Clinical Trials

News
  1. Ongoing Clinical Trials
  2. Trial results
  3. Clinical Trials at Google
  1. Amitriptyline in the news
  2. Be alerted on news
  3. News trends

Definition - Amitriptyline

Social media posts - Amitriptyline
  1. Definitions
Flickr

Books on the topic

Bing.png
  1. Books on Amitriptyline
  2. Amazon on Amitriptyline
Facebook posts
Tumblr

Continuing medical education (CME)

Quora.png
  1. CME Programs
Tweets
Commentary & Blogs
Yelp.png
  1. Blogs
  2. Commentary
  3. FAQ
  4. .Gov
  5. PDF files
YouTube videos
Pins
Instagram.png
Reddit
External:W8MD Weight Loss, Sleep & MedSpa Wellness Topics A-Z
W8md-logo.jpg

A | B | C | D | E | F | G

H | I | J | K | L | M | N

O | P | Q | R | S | T | U

V | W | X | Y | Z

WikiMD Sponsors: W8MD Weight Loss, Sleep & Medical Aesthetics


W8MD weight loss

Tired of being overweight or obese? W8MD's insurance weight loss program can HELP

  • W8MD IV Nutrition: Our IM and IV nutrition therapy includes booster shots for B12, vitamin B complex, Vitamin C, Detox treatments and IV nutrition therapy. learn more…
W8MD weight loss locations: Philadelphia weight loss | King of Prussia, PA weight loss | NYC weight loss | NJ weight loss

Medical Aesthetics

Contact us (718) 946-5501 | Why advertise on WikiMD?


Disclaimer: The entire contents of WIKIMD.ORG are for informational purposes only and do not render medical advice or professional services. If you have a medical emergency, you should CALL 911 immediately! Given the nature of the wiki, the information provided may not be accurate and or incorrect. Use the information on this wiki at your own risk! See full Disclaimers.WikiMD is supported by W8MD Weight loss, Poly-Tech Sleep & Medical Aesthetic Centers of America.