Cardiomyopathy

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Cardiomyopathy represents a collection of diverse conditions of the heart muscle. These diseases have many causes, symptoms, and treatments and can affect people of all ages and races.

When cardiomyopathy occurs, the normal muscle in the heart can thicken, stiffen, thin out, or fill with substances the body produces that do not belong in the heart muscle. As a result, the heart muscle’s ability to pump blood is reduced, which can lead to irregular heartbeats, the backup of blood into the lungs or rest of the body, and heart failure.

Cardiomyopathy can be acquired—developed because of another disease, condition, or factor—or inherited. The cause isn’t always known.

The main types of cardiomyopathy include the following 1-4:

  • Dilated cardiomyopathy: where one of the pumping chambers (ventricles) of the heart is enlarged. This is more common in males and is the most common form of cardiomyopathy in children. It can occur at any age and may or may not be inherited.
  • Hypertrophic: where the heart muscle is thickened. This often presents in childhood or early adulthood and can cause sudden death in adolescents and young adult athletes.1 It is often an inherited condition, and a person may not have any symptoms. If there is a family history of this, other family members can be tested and adjust their activities to reduce the risk of sudden death.
  • Arrhythmogenic: where the disease causes irregular heartbeats or rhythms. This is often inherited and more common in males.

Restrictive: where heart muscle is stiff or scarred, or both. It can occur with amyloidosis or hemochromatosis, and other conditions. This is the least common type.

  • Hypertrophic cardiomyopathy is thought to be the most common inherited or genetic heart disease. While this type of cardiomyopathy occurs at many ages, in children and young adults with this condition there may be no symptoms, yet they are at high risk of sudden cardiac death.

Causes of cardiomyopathy

Although the cause of cardiomyopathy is sometimes unknown, certain diseases or conditions can lead to cardiomyopathy. These include the following:

  • A family history of cardiomyopathy, heart failure or sudden cardiac arrest.
  • Connective tissue disease and other types of autoimmune disease.
  • Coronary heart disease or a heart attack.
  • Diseases that can damage the heart, such as hemochromatosis, sarcoidosis or amyloidosis.
  • Endocrine diseases, including thyroid conditions and diabetes.
  • Infections in the heart muscle.
  • Long-term alcoholism or cocaine abuse.
  • Muscle conditions such as muscular dystrophy.
  • Pregnancy.

Symptoms

Some people who have cardiomyopathy never have symptoms, while others may show signs as the disease progresses. These might include the following:

  • Shortness of breath or trouble breathing.
  • Fatigue.
  • Swelling in the ankles and legs.
  • Irregular heart beat or palpitations.
  • Syncope, the medical term for fainting or briefly passing out.

Treatment and Prevention

The goal of treatment is to slow down the disease, control symptoms, and prevent sudden death. If you are diagnosed with cardiomyopathy, your doctor may tell you to change your diet and physical activity, reduce stress, avoid alcohol and other drugs, and take medicines. Your doctor may also treat you for the conditions that led to cardiomyopathy, if they exist, or recommend surgery. Treatment also depends on which type of cardiomyopathy you have.

Genetic or inherited types of cardiomyopathy cannot be prevented, but adopting or following a healthier lifestyle can help control symptoms and complications. If you have an underlying disease or condition that can cause cardiomyopathy, early treatment of that condition can help prevent the disease from developing.

Pediatric Cardiomyopathy

Cardiomyopathy can occur in children regardless of age, race, and gender. Pediatric cardiomyopathy can be inherited or acquired through a viral infection and sometimes the cause is unknown. It is a frequent cause of sudden cardiac arrest in the young, according to the National Heart, Lung and Blood Institute. Treatment may include medications, changes to physical activity, or surgery.




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