Hashimoto's thyroiditis

From WikiMD free wellness and medical encyclopedia
Jump to: navigation, search

Hashimoto's thyroiditis, the most common form of thyroiditis, is an autoimmune disease where the body's own antibodies fight the cells of the thyroid. Also known as Hashimoto's disease, it is named after the Japanese physician, Hakaru Hashimoto (1881–1934) of the medical school at Kyushu University, who first described the symptoms in 1912. This disorder is believed to be the most common cause of primary hypothyroidism in North America. It is more prevalent (8:1) in women than in men, and its incidence increases with age. A family history of thyroid disorders is common, with the HLADR5 gene most strongly implicated conferring a relative risk of 3 in the UK. The genes implicated vary in different ethnic groups and the incidence is increased in patients with chromosomal disorders, including Turner's, Down, and Klinefelter's syndromes.

In many cases, Hashimoto's thyroiditis usually results in hypothyroidism, although in its acute phase, it can cause a transient hyperthyroid state.

Physiologically, antibodies to thyroid peroxidase and/or thyroglobulin cause gradual destruction of follicles in the thyroid gland. Accordingly, the disease can be detected clinically by looking for these antibodies in the blood. It is also characterised by invasion of the thyroid tissue by leukocytes, chiefly T-lymphocytes.

Treatment is with daily thyroxine, with the sodium salt of thyroxine liothyronine given when the need to raise levels of circulating thyroxine is urgent.

Symptoms of Hashimoto's thyroiditis include symptoms of hypothyroidism and a goitre.

In European countries an atrophic form of autoimmune thyroiditis (Ord's thyroiditis) is more common than Hashimoto's thyroiditis.


Health Topics | Health Encyclopedia | First Aid | Weight Loss | Drugs | Glossary of medicine | Health insurance | Glossary of health topics | Drug classes


Health science - Medicine
Anesthesiology - Dermatology - Emergency Medicine - General practice - Intensive care medicine - Internal medicine - Neurology - Obstetrics & Gynecology - Pediatrics - Podiatry - Public Health & Occupational Medicine - Psychiatry - Radiology - Surgery
Branches of Internal medicine
Cardiology - Endocrinology - Gastroenterology - Hematology - Infectious diseases - Nephrology - Oncology - Pulmonology - Rheumatology
Branches of Surgery
General surgery - Cardiothoracic surgery - Neurosurgery - Ophthalmology - Orthopedic surgery - Otolaryngology (ENT) - Plastic surgery - Podiatric surgery - Urology - Vascular surgery
Popular Health Topics

A |  B |  C |  D |  E |  F |  G |  H |  I |  J |  K |  L |  M | N |  O |  P |  Q |  R |  S |  T |  U |  V |  W |  X |  Y |  Z

Glossary of medical terms | Dictionary of medicine | Drugs A-Z | Topics in Medicine | Dictionary of drugs

Modified from Wikipedia's article licensed under GNU FDL

WikiMD Sponsors: W8MD Weight Loss, Sleep & Medical Aesthetics


Photofacial-before-and-after

Tired of being overweight or obese? W8MD's insurance weight loss program can HELP

  • W8MD IV Nutrition: Our IM and IV nutrition therapy includes booster shots for B12, vitamin B complex, Vitamin C, Detox treatments and IV nutrition therapy. learn more…
W8MD weight loss locations: Philadelphia weight loss | King of Prussia, PA weight loss | NYC weight loss | NJ weight loss

Medical Aesthetics

Contact us (718) 946-5501 | Why advertise on WikiMD?


Disclaimer: The entire contents of WIKIMD.ORG are for informational purposes only and do not render medical advice or professional services. If you have a medical emergency, you should CALL 911 immediately! Given the nature of the wiki, the information provided may not be accurate and or incorrect. Use the information on this wiki at your own risk! See full Disclaimers.WikiMD is supported by W8MD Weight loss, Poly-Tech Sleep & Medical Aesthetic Centers of America.