Breaking news: On November 9th, 2020, the world got a glimmer of hope when the pharmaceutical giant, Pfizer announced that it's COVID 19 vaccine candidate was found to be more than 90% effective in preventing COVID-19 in participants without evidence of prior SARS-CoV-2 infection in the first interim efficacy analysis.
Vaccine development process
The vaccine currently being developed and studied by Pfizer is an RNA vaccine that targets the spike protein, the spiky protrusion on the SARS-CoV-2 virus that allows the virus to attach to and invade human cells, initiating infection.
An RNA vaccine basically consists of an mRNA strand artificially created that codes for a disease-specific antigen which when injected in to the human or animal body, creates an antibody response.
In fact, all of the vaccines being developed by major manufacturers working with Operation Warp Speed, the U.S. government effort to fast-track vaccines, target the spike protein.
The preliminary analysis evaluated 94 confirmed cases of COVID-19 in trial participants.
The study enrolled 43,538 participants, with 42% having diverse backgrounds, and no serious safety concerns have been observed;
Safety and additional efficacy data continue to be collected.
See full press release
Bamlanivimab received an emergency use authorization (EuA)by the FDA for the treatment of mild-to-moderate COVID-19 in adult and pediatric patients.
Bamlanivimab is authorized for patients with positive results of direct SARS-CoV-2 viral testing
Are 12 years of age and older weighing at least 40 kilograms (about 88 pounds), and
Are at high risk for progressing to severe COVID-19 and/or hospitalization including those that are 65 years of age or older, or who have certain chronic medical conditions.
Reduced COVID-19 related hospitalizations
Bamlanivimab was shown in clinical trials to reduce COVID-19-related hospitalization or emergency room visits in patients at high risk for disease progression within 28 days after treatment when compared to placebo.
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Featured disease - Ewing's Sarcoma
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