View source for Template:Chemotherapeutic agents

{{Navbox
 | name = Chemotherapeutic agents
 | title = Intracellular [[Chemotherapy|chemotherapeutic agents]]&nbsp;/ [[Antineoplastic|antineoplastic agents]] ([[ATC code L01|L01]])
 | state = {{{state<includeonly>|collapsed</includeonly>}}}
 | listclass = hlist

 | group1 = [[Spindle poison|SP]]s/[[Mitotic inhibitor|MI]]s<br />([[M phase]])
 | list1 = {{Navbox|child

   | group1 = Block [[microtubule]] assembly
   | list1 =
* ''[[Catharanthus#Vinca alkaloids|Vinca alkaloid]]s'' ([[Vinblastine]]<sup>#</sup>
* [[Vincristine]]<sup>#</sup>
* [[Vindesine]]
* [[Vinflunine]]<sup>§</sup>
* [[Vinorelbine]]<sup>#</sup>)

   | group2 = Block microtubule disassembly
   | list2 =
* ''[[Taxane]]s'' ([[Cabazitaxel]]
* [[Docetaxel]]<sup>#</sup>
* [[Larotaxel]]
* [[Ortataxel]]<sup>†</sup>
* [[Paclitaxel]]<sup>#</sup>
* [[Tesetaxel]])
* ''[[Epothilone]]s'' ([[Ixabepilone]])

 }}

 | group2 = [[DNA replication]]<br />inhibitor
 | list2 = {{Navbox|child

   | group1 = DNA precursors/<br />[[antimetabolite]]s<br />([[S phase]])
   | list1 = {{Navbox|child

     | group1 = [[Antifolate|Folic acid]]
     | list1 =
* ''[[Dihydrofolate reductase inhibitor]]'' ([[Aminopterin]]
* [[Methotrexate]]<sup>#</sup>
* [[Pemetrexed]]
* [[Pralatrexate]])
* ''[[Thymidylate synthase inhibitor]]'' ([[Pemetrexed]]
* [[Raltitrexed]])

     | group2 = [[Purine analogue|Purine]]
     | list2 =
* ''[[Adenosine deaminase inhibitor]]'' ([[Pentostatin]])

* ''[[Halogenation|Halogenated]]/[[ribonucleotide reductase inhibitor]]s'' ([[Cladribine]]
* [[Clofarabine]]
* [[Fludarabine]])
* [[Nelarabine]]

* ''[[Thiopurine]]'' ([[Mercaptopurine]]<sup>#</sup>
* [[Tioguanine]]<sup>#</sup>)

     | group3 = [[Pyrimidine analogue|Pyrimidine]]
     | list3 =
* ''[[Thymidylate synthase inhibitor]]'' ([[Capecitabine]]<sup>#</sup>
* [[Carmofur]]
* [[Doxifluridine]]
* [[Floxuridine]]
* [[Fluorouracil]]<sup>#</sup>
* [[Tegafur]] ([[Tegafur/gimeracil/oteracil|+gimeracil/oteracil]]))

* ''[[DNA polymerase inhibitor]]'' ([[Cytarabine]]<sup>#</sup>)

* ''[[Ribonucleotide reductase inhibitor]]'' ([[Gemcitabine]]<sup>#</sup>)

* ''[[Hypomethylating agent]]'' ([[Azacitidine]]
* [[Decitabine]])

     | group4 = [[Deoxyribonucleotide]]
     | list4 =
* ''[[Ribonucleotide reductase inhibitor]]'' ([[Hydroxycarbamide]]<sup>#</sup>)

   }}

   | group2 = [[Topoisomerase inhibitor]]s<br />([[S phase]])
   | list2 = {{Navbox|child

     | group1 = [[Type I topoisomerase#Inhibition|I]]
     | list1 =
* ''[[Camptotheca]]'' ([[Belotecan]]
* [[Camptothecin]]
* [[Cositecan]]<sup>†</sup>
* [[Exatecan]]
* [[Gimatecan]]
* [[Irinotecan]]<sup>#</sup>
* [[Lurtotecan]]<sup>‡</sup>
* [[Rubitecan]]<sup>‡</sup>
* [[Silatecan]]<sup>§</sup>
* [[Topotecan]])

     | group2 = [[Type II topoisomerase#Inhibition|II]]
     | list2 =
* ''[[Podophyllum peltatum|Podophyllum]]'' ([[Etoposide]]<sup>#</sup>
* [[Teniposide]])

     | group3 = [[Type II topoisomerase#Inhibition|II]]+[[Intercalation (biochemistry)|Intercalation]]
     | list3 =
* ''[[Anthracycline]]s'' ([[Aclarubicin]]
* [[Amrubicin]]<sup>†</sup>
* [[Daunorubicin]]<sup>#</sup>
* [[Doxorubicin]]<sup>#</sup>
* [[Epirubicin]]
* [[Idarubicin]]
* [[Pirarubicin]]
* [[Valrubicin]]
* [[Zorubicin]])
* ''[[Anthraquinone|Anthracenedione]]s'' ([[Mitoxantrone]]
* [[Pixantrone]])

   }}

   | group3 = [[Crosslinking of DNA]]<br />([[Cell-cycle nonspecific antineoplastic agents|CCNS]])
   | list3 = {{Navbox|child
     | evenodd = swap

     | group1 = [[Alkylating antineoplastic agent|Alkylating]]
     | list1 =
* ''[[Nitrogen mustard]]s:'' [[Bendamustine]]<sup>#</sup>
* [[Chlormethine]]
* [[Cyclophosphamide]]<sup>#</sup> ([[Ifosfamide]]<sup>#</sup>
* [[Trofosfamide]])
* [[Chlorambucil]]<sup>#</sup> ([[Melphalan]]
* [[Prednimustine]])
* [[Uramustine]]

* ''[[Nitrosourea]]s:'' [[Carmustine]]
* [[Fotemustine]]
* [[Lomustine]] ([[Semustine]])
* [[Nimustine]]
* [[Ranimustine]]
* [[Streptozotocin|Streptozocin]]

* ''[[Alkyl sulfonate]]s:'' [[Busulfan]] ([[Mannosulfan]]
* [[Treosulfan]])

* ''[[Aziridine]]s:'' [[Carboquone]]
* [[Thiotepa]]
* [[Triaziquone]]
* [[Triethylenemelamine]]

     | group2 = [[Platinum-based antineoplastic|Platinum-based]]
     | list2 =
* [[Carboplatin]]<sup>#</sup>
* [[Cisplatin]]<sup>#</sup>
* [[Dicycloplatin]]
* [[Nedaplatin]]
* [[Oxaliplatin]]<sup>#</sup>
* [[Satraplatin]]

     | group3 = [[Alkylating antineoplastic agent#Nonclassical|Nonclassical]]
     | list3 =
* [[Altretamine]]
* ''[[Hydrazine]]s'' ([[Procarbazine]]<sup>#</sup>)
* [[Mitobronitol]]
* [[Pipobroman]]
* ''[[Triazene]]s'' ([[Dacarbazine]]<sup>#</sup>
* [[Temozolomide]])

     | group4 = [[Intercalation (biochemistry)|Intercalation]]
     | list4 =
* [[Streptomyces]] ([[Actinomycin]]<sup>#</sup>
* [[Bleomycin]]<sup>#</sup>
* [[Mitomycins]]
* [[Plicamycin]])

   }}
 }}

<!-- group3 omitted to preserve alternating striping -->

 | group4 = [[Photosensitizer]]s/[[Photodynamic therapy|PDT]]
 | list4 =
* [[Aminolevulinic acid]]&nbsp;/ [[Methyl aminolevulinate]]
* [[Efaproxiral]]
* [[Padeliporfin]]
* ''[[Porphyrin|Porphyrin derivatives]]'' ([[Porfimer sodium]]
* [[Talaporfin]]
* [[Temoporfin]]
* [[Verteporfin]])

 | group5 = Other
 | list5 = {{Navbox|child

   | group1 = [[Enzyme inhibitor]]s
   | list1 =
* ''[[Farnesyltransferase inhibitor|FI]]'' ([[Tipifarnib]]<sup>§</sup>)
* ''[[Cyclin-dependent kinase|CDK]] [[Protein kinase inhibitor|inhibitor]]s'' ([[Abemaciclib]]
* [[Alvocidib]]<sup>†</sup>
* [[Palbociclib]]
* [[Ribociclib]]
* [[Seliciclib]]<sup>†</sup>)
* ''[[Proteasome inhibitor|PrI]]''
** [[Bortezomib]]
** [[Carfilzomib]]
** [[Ixazomib]]
* ''[[Phosphodiesterase inhibitor|PhI]]'' ([[Anagrelide]])
* ''[[IMP dehydrogenase|IMPDI]]'' ([[Tiazofurin]]<sup>§</sup>)
* ''[[Lipoxygenase inhibitor|LI]]'' ([[Masoprocol]])
* ''[[PARP inhibitor]]'' ([[Niraparib]]
* [[Olaparib]]
* [[Rucaparib]])
* ''[[Histone deacetylase inhibitor|HDAC]]'' ([[Belinostat]]
* [[Panobinostat]]
* [[Romidepsin]]
* [[Vorinostat]])
* ''[[Phosphoinositide 3-kinase inhibitor|PIKI]]'' ([[Alpelisib]]
* [[Idelalisib]])

   | group2 = [[Receptor antagonist]]s
   | list2 =
* ''[[Endothelin receptor antagonist|ERA]]'' ([[Atrasentan]])
* ''[[Retinoid X receptor]]'' ([[Bexarotene]])
* ''[[Sex steroid]]'' ([[Testolactone]])

   | group3 = Other/ungrouped
   | list3 =
* [[Amsacrine]]
* [[Arsenic trioxide]]
* ''[[Asparagine|Asparagine depleter]]s'' ([[Asparaginase]]<sup>#</sup>/[[Pegaspargase]])
* [[Celecoxib]]
* [[Demecolcine]]
* [[Elesclomol]]<sup>§</sup>
* [[Elsamitrucin]]
* [[Eribulin]]
* [[Estramustine phosphate]]
* [[Etoglucid]]
* [[Lonidamine]]
* [[Lucanthone]]
* [[Mitoguazone]]
* [[Mitotane]]
* [[Oblimersen]]<sup>†</sup>
* [[Omacetaxine mepesuccinate]]
* [[Trabectedin]]
* ''[[Retinoid]]s'' ([[Alitretinoin]]
* [[Tretinoin]]<sup>#</sup>)
* [[Venetoclax]]

 }}

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 | below = {{PharmNavFootnote}}

}}<noinclude>
{{collapsible option}}
[[Category:Drug templates by ATC]]
[[Category:Oncology templates]]
</noinclude>