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11c-sarcosine - a radiotracer consisting of sarcosine, the n-methyl derivative of the amino acid glycine, labeled with the positron-emitting isotope carbon c 11, that can be used for tumor imaging upon positron emission tomography/computed tomography (pet/ct). Upon administration, c-11 sarcosine is taken up by and accumulates in tumor cells, thereby allowing tumor imaging with pet/ct. Sarcosine, a non-proteinogenic amino acid and oncometabolite, is elevated in certain tumor cell types. Its expression seems to correlate with increased tumor invasiveness. Also see carbon c 11 sarcosine

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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on 11c-sarcosine for any updates.


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