131I-MIBG
131I-MIBG
131I-MIBG (pronunciation: one-thirty-one I-M-I-B-G), also known as Iodine-131 metaiodobenzylguanidine, is a radiopharmaceutical used in medical imaging and therapy, particularly in the fields of oncology and nuclear medicine.
Etymology
The term 131I-MIBG is an abbreviation derived from the compound's full chemical name, Iodine-131 metaiodobenzylguanidine. The "131I" refers to the radioactive isotope of iodine used, while "MIBG" stands for metaiodobenzylguanidine, a synthetic analogue of the neurotransmitter norepinephrine.
Usage
131I-MIBG is primarily used in the diagnosis and treatment of certain types of cancer, including neuroblastoma, pheochromocytoma, and paraganglioma. It works by mimicking norepinephrine, allowing it to be taken up by neuroendocrine tumors that usually take up this neurotransmitter. Once inside the tumor cells, the radioactive iodine emits radiation that can kill the cells.
Related Terms
- Radiopharmaceutical: A radioactive compound used in diagnosis or therapy.
- Nuclear Medicine: A medical specialty involving the application of radioactive substances in the diagnosis and treatment of disease.
- Oncology: The study and treatment of tumors.
- Neuroblastoma: A cancer that develops from immature nerve cells found in several areas of the body.
- Pheochromocytoma: A rare tumor that usually starts in the cells of one of your adrenal glands.
- Paraganglioma: Rare neuroendocrine neoplasms that may develop at various body sites.
External links
- Medical encyclopedia article on 131I-MIBG
- Wikipedia's article - 131I-MIBG
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