4-18F fluoroglutamic acid

From WikiMD's free health, diet & wellness encyclopedia
Jump to navigation Jump to search

A radioconjugate composed of the radionuclide fluorine F 18 conjugated to L-glutamic acid, with potential imaging activity upon positron emission tomography (PET). Upon intravenous administration, the glutamic acid moiety of 4-[18F]fluoroglutamic acid specifically binds to tumor cells and is preferentially taken up by tumor cells due to the higher metabolic activity and enhanced glutaminolytic pathway in these cells compared to normal, healthy cells. Upon internalization and PET, tumor cells can be imaged and assessed. Tumor cells use the amino acid glutamine for nutritional purposes necessary for energy production and growth; as tumor cells proliferate more rapidly than normal healthy cells, glutamine uptake is higher in certain cancer cells.

Learn more about 4-18F fluoroglutamic acid

Latest research - 4-18F fluoroglutamic acid

PubMed
Clinical trials

External links

Wikipedia
Medicine icon
Medicine icon

This WikiMD article 4-18F fluoroglutamic acid is a stub. If you are familiar with the topic 4-18F fluoroglutamic acid, you can help us. Paid editors welcome!

 

4-18F fluoroglutamic acid is part of WikiMD's free ^articles!

^4-18F fluoroglutamic acid (article) is provided for informational purposes only. No expressed or implied warranties as to the validity of content.
WikiMD is not a substitute for professional advice. By accessing and using WikiMD you agree to the terms of use.
Templates etc. when imported from Wikipedia, are licensed under CC BY-SA 3.0. See full disclaimers.
W8MD weight loss logo

Ad. Tired of being overweight?. W8MD's physician weight loss program can HELP. Tele medicine available