Anticardiolipin antibody
Anticardiolipin antibody (an-ti-kar-dee-o-lip-in an-ti-bod-ee) is a type of autoantibody that is often associated with antiphospholipid syndrome.
Etymology
The term "anticardiolipin" is derived from the words "anti-", meaning against, and "cardiolipin", a type of phospholipid that is a major component of the inner mitochondrial membrane, which plays an important role in the electron transport chain and serves as an antigenic target of these antibodies.
Definition
Anticardiolipin antibodies are autoantibodies, produced by the immune system, that mistakenly target one's own cardiolipin, a phospholipid that plays a key role in the coagulation pathway.
Clinical Significance
The presence of anticardiolipin antibodies can lead to an increased risk of blood clots, miscarriage, or other complications during pregnancy. They are often found in individuals with antiphospholipid syndrome, a disorder that can cause blood clots in arteries and veins, and complications in pregnancies.
Related Terms
See Also
External links
- Medical encyclopedia article on Anticardiolipin antibody
- Wikipedia's article - Anticardiolipin antibody
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