Churg Strauss syndrome
Churg Strauss Syndrome
Churg Strauss Syndrome (pronounced: churg strauss sin-drome), also known as Eosinophilic Granulomatosis with Polyangiitis (EGPA), is a rare autoimmune condition characterized by inflammation of small to medium-sized blood vessels (vasculitis) in persons with a history of airway allergic hypersensitivity (atopy).
Etymology
The syndrome is named after Jacob Churg and Lotte Strauss, the pathologists who first described the condition in 1951.
Symptoms
The symptoms of Churg Strauss Syndrome can vary greatly from person to person, but may include asthma, sinusitis, skin rashes, and peripheral neuropathy. In severe cases, the disease can cause life-threatening complications such as heart disease and kidney damage.
Diagnosis
Diagnosis of Churg Strauss Syndrome is based on a combination of clinical symptoms, laboratory tests including blood tests for eosinophilia and ANCA, and biopsy of affected tissues.
Treatment
Treatment typically involves corticosteroids to reduce inflammation and suppress the immune system, and in severe cases, immunosuppressive drugs may be used.
Prognosis
The prognosis for Churg Strauss Syndrome can vary depending on the severity of the disease and the organs involved. With appropriate treatment, many people with the disease can lead normal lives.
See also
References
External links
- Medical encyclopedia article on Churg Strauss syndrome
- Wikipedia's article - Churg Strauss syndrome
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