ROS1 positive

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ROS1 positive
TermROS1 positive
Short definitionROS1 positive - Describes cells that have a protein called ROS1 on their surface. In the case of cancer, this also refers to cells that have a change in the structure of the ROS1 gene or a ROS1 fusion protein on their surface. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


ROS1 positive - Describes cells that have a protein called ROS1 on their surface. In the case of cancer, this also refers to cells that have a change in the structure of the ROS1 gene or a ROS1 fusion protein on their surface. In normal cells, ROS1 is involved in cell signaling and cell growth. Cancer cells that have the altered ROS1 gene or ROS1 fusion protein can grow faster. Knowing whether a cancer is ROS1 positive can be helpful in planning treatment. Cancers that can be ROS1 positive include non-small cell lung cancer, a type of brain tumor called glioblastoma multiforme, and cancers of the bile duct, ovaries, stomach, colon, and rectum

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