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  • ...ounced tri-la-ci-clib) is a small molecule inhibitor of [[Cyclin-dependent kinases]] (CDK) 4 and 6. It is developed by [[G1 Therapeutics]] and is used in the ...t is part of the drug's structure), and "clib" (an abbreviation of "cyclin-dependent kinase inhibitor").
    2 KB (229 words) - 00:20, 7 February 2024
  • ...r) is a family of proteins that function as inhibitors of cyclin-dependent kinases (CDKs). The name INK4 is an acronym derived from '''I'''nhibitors of '''C'' ...of the proteins in this family. They are known to inhibit cyclin-dependent kinases, particularly CDK4, hence the name INK4.
    2 KB (257 words) - 04:14, 4 February 2024
  • ...ifically designed to target and inhibit the activity of [[cyclin-dependent kinases]] (CDKs). It is currently under investigation for its potential use in the ...in kinases]] that are crucial for cell cycle regulation. By blocking these kinases, Seliciclib can halt the progression of the cell cycle, thereby inhibiting
    1 KB (181 words) - 04:38, 6 February 2024
  • ...RNA, and 'ciclib' is a suffix used for drugs that inhibit cyclin-dependent kinases (CDKs). ...s. In many types of cancer, uncontrolled cell division is driven by CDK4/6-cyclin D complexes. Ribociclib inhibits the proliferation of these cancer cells by
    1 KB (204 words) - 04:47, 6 February 2024
  • ...the field of [[oncology]]. It is a potent inhibitor of [[cyclin-dependent kinases]] (CDKs), which are enzymes that play a crucial role in cell cycle regulati * [[Cyclin-dependent kinases]] (CDKs): A family of protein kinases first discovered for their role in regulating the cell cycle.
    1 KB (176 words) - 14:25, 5 February 2024
  • ...ese include [[Cyclin|cyclins]], [[Cyclin-dependent kinase|cyclin-dependent kinases (CDKs)]], and [[Tumor suppressor|tumor suppressors]].
    2 KB (236 words) - 22:43, 14 February 2024