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- ...ic disorder]] characterized by its three main symptoms: [[pyogenic sterile arthritis]], [[pyoderma gangrenosum]], and [[acne]]. The syndrome is caused by mutati ...itial letters of the three main symptoms of the syndrome: Pyogenic sterile Arthritis, Pyoderma gangrenosum, and Acne.2 KB (254 words) - 23:46, 8 February 2024